Estudio revela que el zika podría causar meningoencefalitis en adultos
on marzo 10, 2016 4:19 pm .
Publicado en La Patilla: Actualidad, Internacionales
El virus del Zika podría causar meningoencefalitis en adultos, una peligrosa inflamación de las meninges y el cerebro, según un nuevo estudio que publica hoy la revista especializada "The New England Journal of Medicine".
EFE
Esta es la conclusión de un grupo de científicos franceses tras descubrir que un hombre de 81 años infectado de zika en un crucero en el Pacífico Sur, donde circula el virus, desarrolló meningoencefalitis y no se recuperó hasta pasado un mes.
"Los médicos deben estar al tanto de que el virus del Zika puede estar asociado con la meningoencefalitis", advierten los autores del estudio.
Varios virus pueden causar meningitis, encefalitis y la combinación de ambas, entre ellos el virus del Nilo Occidental, transmitido por un mosquito diferente al del zika.
Los científicos descartaron que el paciente de 81 años tuviera cualquier otro virus y detectaron Zika en su líquido cefalorraquídeo.
El hombre no tuvo ningún problema de salud durante las cuatro semanas que duró el crucero, pero 10 días después de terminar el viaje lo ingresaron en la Unidad de Cuidados Intensivos (UCI) con varias dolencias graves, entre ellas un estado comatoso medio.
El paciente desarrolló fiebre alta y tuvo un sarpullido en las siguientes 48 horas, ambos síntomas de varios virus, entre ellos el Zika.
Hasta ahora, el posible vínculo del zika con la microcefalia, otras malformaciones congénitas y el síndrome de Guillain-Barré han sido los temas más urgentes en la investigación científica sobre el actual brote del virus, que afecta sobre todo a América Latina.
La comunidad científica espera tener en los próximos tres o cuatro meses los primeros estudios que arrojen luz sobre la vinculación del zika con las malformaciones congénitas y los trastornos neurológicos, así como otras posibles complicaciones de salud asociadas al virus.
Solo Brasil y la Polinesia Francesa han reportado casos de microcefalia (bebés con un cerebro de tamaño menor de lo normal) vinculados al zika, pero la Organización Panamericana de la Salud OPS) prevé que en los próximos meses se identifiquen los primeros casos en Colombia, donde el brote se detectó en octubre.
En seis países o territorios se ha detectado un incremento de casos del síndrome de Guillain-Barré posiblemente asociado al virus: Brasil, Polinesia Francesa, El Salvador, Colombia, Venezuela y Surinam.
The New England Journal of Medicine
Zika Virus Collection
A collection of articles and other resources on the Zika virus outbreak, including clinical reports, management guidelines, and commentary.
Sharing Data in a Public Health Emergency
The case for sharing data, and the consequences of not doing so, have been brought into stark relief by the Ebola and Zika outbreaks. In response, the New England Journal of Medicine has become a journal signatory to the following statement.
"In the context of a public health emergency of international concern, it is imperative that all parties make available any information that might have value in combatting the crisis. As research funders and journals, we are committed to working in partnership to ensure that the global response to public health emergencies is informed by the best available research evidence and data.
Journal signatories will make all content concerning the Zika virus free access. Any data or preprint deposited for unrestricted dissemination ahead of submission of any paper will not preempt later publication in these journals.
Funder signatories will require researchers undertaking work relevant to public health emergencies to establish mechanisms to share quality-assured interim and final data as rapidly and widely as possible, including with public health and research communities and the World Health Organization.
We urge other journals and research funders to make the same commitments."
correspondence
March 9, 2016 | G. Carteaux and Others
(DOI: 10.1056/NEJMc1602964)
As Zika virus spreads, the associated clinical syndromes need to be defined. In this report, an 81-year-old man is found to have Zika virus–associated meningoencephalitis.
Perspective
March 9, 2016 | N. Broutet and Others
(DOI: 10.1056/NEJMp1602708)
As researchers investigate whether and by what mechanisms Zika virus infections could affect the nervous system, there is a key question for public health: How can currently available evidence about causality guide the choice and implementation of interventions?
Perspective
March 9, 2016 | D.L. Heymann, J. Liu, and L. Lillywhite
(DOI: 10.1056/NEJMp1602278)
Collaborative research could most effectively answer critical research questions about Zika, microcephaly, and other neurologic disorders and help to enhance global health security. Yet collaborative research is not a given.
original article
March 4, 2016 | P. Brasil and Others
(DOI: 10.1056/NEJMoa1602412)
Zika virus is spreading rapidly in the Americas and the Caribbean. Concerns about its teratogenic potential are increasing. In pregnant women with evidence of acute Zika virus infection in Rio de Janeiro, ultrasound evidence of fetal abnormalities was seen in over 25%.
brief report
March 10, 2016 | J. Mlakar and Others
Published Online: February 10, 2016
Zika virus is an emerging infectious disease that is spreading rapidly through the Americas. A major concern is the association with birth defects, especially microcephaly. This report shows evidence of Zika virus in the fetal brain.
· Free Full Text
Perspective
February 18, 2016 | A.S. Fauci and D.M. Morens
Published Online: January 13, 2016
The explosive pandemic of Zika virus infection in South and Central America is the most recent of four unexpected arrivals of important arthropod-borne viral diseases in the Western Hemisphere over the past 20 years. Is this an important new disease-emergence pattern?
· Free Full Text
original article
June 11, 2009 | M.R. Duffy and Others
Zika virus is a flavivirus known to cause human infection in Asia and Africa. This article describes an outbreak of Zika virus infection on Yap Island, Federated States of Micronesia, with predominant symptoms of rash, fever, arthralgia, and conjunctivitis. An estimated 73% of Yap residents 3 years of age or older became infected during the 4 months of the outbreak.
· Free Full Text
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